RESUMO
Eosinophilic folliculitis is considered a heterogeneous group of disorders, with several clinical subsets, sharing a common histopathological appearance. Increasing numbers of cases, following bone marrow transplantation (BMT), have been reported in recent years. We herein present a case of eosinophilic folliculitis that appeared in a 26-year-old woman 5 months after allogeneic peripheral blood stem cell transplantation as treatment for eosinophilic acute leukemia. Our review of the published cases has shown that eosinophilic folliculitis in patients after BMT could be considered as a pattern of reaction related to immune dysregulation.
Assuntos
Eosinofilia/etiologia , Foliculite/etiologia , Transplante de Células-Tronco de Sangue Periférico/efeitos adversos , Adulto , Anti-Inflamatórios/uso terapêutico , Eosinofilia/tratamento farmacológico , Eosinofilia/patologia , Feminino , Foliculite/tratamento farmacológico , Foliculite/patologia , Humanos , Leucemia Eosinofílica Aguda/terapia , Prednisona/uso terapêutico , Transplante Homólogo , Resultado do TratamentoRESUMO
On the example of a patients with eosinophil leukaemia, which at first was manifested as eosinophilia in the peripheral blood stream and bone marrow without involvement of other organs and only after three years acquired the character of malignant growth, the authors draw attention to difficulties in the differential diagnosis of hypereosinophil syndrome. At the same time the authors review briefly views on the origin of eosinophil leukaemia, morphological and cytogenetic findings considered useful as evidence of this rare type of leukaemia.
